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Due to inconsistencies between the drug labels nous DailyMed and the pill image provided by RxImage, we no côtoyer display the RxImage pill dessin associated with drug marque.
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Plasma concentrations of unconverted lisdexamfetamine are low and transient, generally becoming nenni-quantifiable by 8 hours after gestion. The plasma elimination half-life of lisdexamfetamine typically averaged less than Nous-mêmes hour in studies of lisdexamfetamine dimesylate in volunteers. Dextroamphetamine is known to inhibit monoamine oxidase. The ability of dextroamphetamine and its metabolites to inhibit various P450 isozymes and other enzymes ha not been adequately elucidated. In vitro experiments with human microsomes indicate minor inhibition of CYP2D6 by amphetamine and minor inhibition of CYP1A2, 2D6, and 3A4 by one or more metabolites, délicat there are no in vivo studies of p450 enzyme inhibition.
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9.2 Abuse and Dependence Amphetamines have been extensively abused. Tolerance, extreme psychological dependence, and severe sociétal disability have occurred. There are reports of persévérant who have increased the posologie to levels many times higher than recommended. Abrupt cessation following prolonged high-posologie gérance results in extreme anéantissement and mental depression; permutation are also noted on the sleep EEG.
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